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Cayman Chemical DRB, 53-85-0, 50 mg
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Supplier:  Cayman Chemical 1001030250

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Molecular Formula C12H12Cl2N2O4, Purity ≥98%, Formula Weight 319.1, Synonyms: 5,6-dichloro-1-β-D-ribofuranosyl-1H-benzimidazole, NSC 401575, Benzimidazole; Inhibits CKII (IC50 range of 4-10 M), Cdk7 (IC50 = ~20 M), Cdk8 (IC50 = ~20 M), and Cdk9 (IC50 = 3 M); inhibits elongation during RNA polymerase II transcription; triggers p53-dependent apoptosis of human colon adenocarcinoma cells; inhibits trans-activated transcription of the Tat protein of HIV-1 (IC50 = ~4 M)

Catalog No. NC9855607


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