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Cayman Chemical DrospIrenon 50mg

Supplier: Cayman Chemical 2334750 MG

An inhibitor of IRE1a inhibits ER stress induced XBP1 splicing and reduces expression of the XBP1 target genes SEC61A1 p58IPK and ERdj4 in RPMI 8226 cells cytotoxic to multiple myeloma cell lines but has no effect on normal mononuclear cells reduces tumor growth and XBP1 splicing in an RPMI 8226 mouse xenograft model (100 mg/kg)
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