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Selleck Chemical LLC (E/Z)-BCI 25mg 15982-84-0 BCI, NSC 150117
Supplier: Selleck Chemical LLC S005625MG
(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 ?M and 8.0 ?M for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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