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Medchemexpress LLC Dub-in-3 | 924296-17-3 | 99.0% | C16H9N5O | 50 MG
Supplier: Medchemexpress LLC HY5073750MG
DUB-IN-3 (compound 22c) is a potent and selective inhibitor of the deubiquitinating enzyme USP8 with an IC50 value of 0.56 μM. It is promising for research in various disease areas including cancer, neurodegenerative diseases, inflammation, viral infection, and cardiovascular disease. In vitro, DUB-IN-3 affects the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC50 values in the 0.5-1.5 μM range.
- Potent and selective inhibitor of USP8
- IC50 value of 0.56 μM for USP8
- Shows promise for cancer research
- Potential in neurodegenerative diseases research
- Relevant for inflammation and viral infection studies
- Affects HCT116 colon and PC-3 prostate cancer cell lines viability
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