Medchemexpress LLC (E)-1-(4-methoxyphenyl)-3-(4-morpholin-4-yl-6-nitroquinolin-2-yl)prop-2-en-1-one | 2313528-04-8 | 97.0% | C23H21N3O5 | 10MG

Supplier:  Medchemexpress LLC HY13569110MG

hnRNPK-IN-1 is a small-molecule ligand that binds heterogeneous nuclear ribonucleoprotein K (hnRNPK), disrupting hnRNPK interaction with the c-myc promoter to inhibit c-myc transcription and induce apoptosis in cell-based assays. Binding affinities were measured by SPR and MST, and the compound is supplied as a solid for research use.

• Binds hnRNPK and disrupts hnRNPK-c-myc promoter interaction.
• Inhibits c-myc transcription and induces apoptosis in HeLa cell assays.
• Measured binding affinities: SPR Kd 4.6 μM, MST Kd 2.6 μM.
• High purity (97.0%) solid, brown to orange in appearance.
• Soluble in DMSO (~5 mg/mL) with warming and sonication.
• Store powder at -20°C (long-term) and solvent solutions at -80°C when possible.

Catalog No. 50-002-59794