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Medchemexpress LLC (E/Z)-GSK5182 | 2699724-40-6 | 98.9% | 417.54 | 100 MG
Supplier: Medchemexpress LLC HY111226A50MG
(E/Z)-GSK5182 is a racemic compound comprised of both (E)-GSK5182 and (Z)-GSK5182 isomers. This compound functions as a highly selective and orally active inverse agonist of estrogen-related receptor γ (ERRγ), exhibiting an IC50 of 79 nM. Additionally, (E/Z)-GSK5182 has been observed to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma cells.
- Racemic compound of (E)-GSK5182 and (Z)-GSK5182 isomers.
- Highly selective.
- Orally active inverse agonist of estrogen-related receptor γ.
- Induces reactive oxygen species generation in hepatocellular carcinoma.
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