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Medchemexpress LLC (E/Z)-mirin | 299953-00-7 | MFCD05885480 | 99.2% | 220.25 | C10H8N2O2S | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1176935MG

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(E/Z)-Mirin is a research reagent that inhibits the Mre11-Rad50-Nbs1 (MRN) complex, blocking MRN-dependent activation of ATM and impairing homology-directed DNA repair. It is supplied as a solid mixture of (E)- and (Z)-isomers for use in cell biology and DNA damage response studies.

  • Inhibits MRN-dependent ATM activation and downstream phosphorylation events.
  • Reported to inhibit H2AX phosphorylation (IC50 ≈ 66 μM).
  • Mixture of (E) and (Z) isomers for research applications.
  • High purity solid suitable for laboratory assays and cellular studies.
  • Stable when stored sealed away from moisture and light; recommended cold storage for solutions.

Catalog No. 50-002-28158


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