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Medchemexpress LLC Edelinontrine | 1082744-20-4 | C20H25N7O2 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY15441100MG

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Edelinontrine (PF-04447943) is a potent and highly selective inhibitor of human recombinant PDE9A. It exhibits an IC50 of 12 nM for PDE9A, showing over 78-fold selectivity compared to other PDE family members.

  • Potent inhibitor of human recombinant PDE9A.
  • Demonstrates high selectivity over other PDE enzymes.
  • Inhibits ANP stimulated cGMP in HEK whole cells expressing rhesus PDE9A2.
  • Increases blood, brain, and cerebrospinal fluid concentrations in rats.
  • Increases CSF cGMP levels in mice.

Catalog No. 50-003-76631


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