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Medchemexpress LLC Edicotinib (JNJ-40346527) | 1142363-52-7 | 99.7% | 461.60 | 100 MG
Supplier: Medchemexpress LLC 100MGHY109086
Edicotinib (JNJ-40346527) is a potent, selective, brain penetrant, and orally active colony-stimulating factor-1 receptor (CSF-1R) inhibitor. It exhibits lower inhibitory effects on KIT and FLT3. This compound limits microglial expansion, attenuates microglial proliferation, and reduces neurodegeneration in mice. It holds potential for research into Alzheimer's disease and rheumatoid arthritis.
- Potent and selective CSF-1R inhibitor
- Brain penetrant and orally active
- Limits microglial expansion
- Attenuates microglial proliferation
- Reduces neurodegeneration in mice
- Potential for Alzheimer's disease and rheumatoid arthritis research
- Available in solid form, white to off-white appearance
- Ships at room temperature
- Multiple solubility protocols for in vitro and in vivo studies
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