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Medchemexpress LLC EGFR-IN-69 | 2433837-65-9 | C31H37Cl2N7O3S | 5 MG
Supplier: Medchemexpress LLC HY1506105MG
EGFR-IN-69 (compound 17g) is a potent EGFR inhibitor used in non-small-cell-lung-cancer (NSCLC) research. It demonstrates strong inhibitory activity against multiple EGFR mutations, including EGFRL858R/T790M/C797S (IC50 4.3 nM), EGFRL858R/T790M (IC50 6.6 nM), and EGFR19del/T790M/C797S (IC50 25.6 nM). The compound also shows antiproliferative and cytotoxic effects on BaF3 cell lines.
- Potent EGFR inhibitor
- Inhibits EGFR L858R/T790M/C797S, L858R/T790M, and del19/T790M/C797S mutations
- Used in NSCLC research
- Antiproliferative and cytotoxic activity against BaF3 cell lines
- Light yellow to yellow solid
- 99.58% purity
- For research use only
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