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ATCC Eker Leiomyoma Tumor-3 (ELT3) cell line (ATCC CRL-3371)
Supplier: ATCC CRL3371
Eker Leiomyoma Tumor-3 (ELT3) is an epithelial-like rat uterine leiomyoma cell line derived from Rattus norvegicus. It carries a germline Tsc2 (TscEk/+) defect with loss of TSC2 tumor suppressor function and is used to study TSC2-related tumor biology and 3D cell culture models.
- Species: Rattus norvegicus (rat)
- Tissue: uterus (leiomyoma)
- Morphology: epithelial-like
- Genetic feature: germline Tsc2 defect with loss of TSC2
- Growth medium: DF8 (DMEM:F12-based medium with defined supplements)
- Culture conditions: 37°C, 5% CO2 in air
- Karyotype: diploid
- Typical applications: studies of TSC2 biology and 3D cell culture
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