Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000440012

Medchemexpress LLC Elexacaftor | 2216712-66-0 | 597.65 | 10 MM 1 ML
SDP

Supplier:  Medchemexpress LLC HY11177210MM/1ML

Encompass_Preferred

Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). It facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface. This next-generation CFTR corrector is designed to restore Phe508del CFTR protein function and has the potential to treat cystic fibrosis.

  • Orally active and highly potent CFTR corrector.
  • Restores processing and trafficking of F508del CFTR protein to the cell surface in human bronchial epithelial (HBE) cells.
  • Binds to F508del CFTR protein and acts as a proteostasis corrector.
  • Can be used for cystic fibrosis research.

Catalog No. 50-004-40012


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.