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BioVendor, LLC IGFBP-3 Total Human ELISA (96 wells)
Supplier: BioVendor, LLC E03A
IGFBP-3 Total Human ELISA (96 wells). A sensitive enzyme immunoassay kit for measuring Insulin-Like Growth Factor Binding Protein-3 in human serum and plasma. QC controls included. No sample pretreatment required. SAMPLE REQUIREMENT: 10 l/well. CALIBRATION RANGE: 0.430 ng/ml. ASSAY RANGE: 0.03 15150 ng/mL. DETECTION LIMIT: 0.1 ng/ml. SUMMARY: As the most abundant IGFBP in circulation, IGFBP3 is of special relevance in regulation of IGF effects. This is reflected by the indicative value of serum IGFBP3 concentration in diagnostics of growth disturbances. Regulation is effected e.g. through nourishing situation; ex. Different diets affect the IGFBP3 concentration. IGFBP3 is able to induce apoptosis, promote tumor growth and inhibit cellular migration and metastasis dependent on tissue and tumor stage. IGFBP3 measurement is useful in the study of growth disorders, ex. growth hormone (GH) deficiency, etc. NAMES: BP-53, IBP3, IBP-3. Manufactured by Mediagnost GmbH, Germany.
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