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Medchemexpress LLC ELOVL6-IN-4 | 1170321-92-2 | C20H20F3N3O3S | 1 ML
Supplier: Medchemexpress LLC HY15294710MM/1ML
ELOVL6-IN-4 is a potent, selective, and orally active long chain fatty acid elongase 6 (ELOVL6) inhibitor. It exhibits IC50s of 79 nM and 94 nM for human and mouse ELOVL6, respectively, showing excellent selectivity over other human ELOVL subtypes and mouse ELOVL3. This compound is for research use only.
- Potent, selective, and orally active long chain fatty acid elongase 6 inhibitor
- Inhibits human ELOVL6 with an IC50 of 79 nM
- Inhibits mouse ELOVL6 with an IC50 of 94 nM
- Shows excellent selectivity over ELOVL1, ELOVL2, ELOVL3, and ELOVL5 subtypes
- Potently reduces elongation index in mouse hepatocyte cells H2.35 with an IC50 of 30 nM
- Suppresses elongation index in the liver in mice in vivo
- Purity of 98.36%
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