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Medchemexpress LLC Emd534085 | 858668-07-2 | 99.55% | 476.53 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY15000100MG

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EMD534085 is a potent and selective inhibitor of the mitotic kinesin-5 with an IC50 of 8 nM. It is intended for research use only. This product offers:

  • Potently and selectively inhibits mitotic kinesin-5.
  • Does not inhibit other tested kinesins at 1 μM or 10 μM.
  • Binds to the allosteric pocket of kinesin-5.
  • Induces rapid cell death in HL60 cells during mitotic arrest.
  • Exhibits antiproliferative activity against human HCT116 cells with an IC50 of 30 nM.
  • Leads to significant tumor growth reduction in mice without toxic side effects.

Catalog No. 50-003-60243


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