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Medchemexpress LLC Encaleret (CLTX-305) | 787583-71-5 | 99.9% | C29H33ClFNO4 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1440150MG

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Encaleret (CLTX-305) is an orally active antagonist of the calcium-sensing receptor (CaSR) with an IC50 of 12 nM. It works by inhibiting the excessive activity of functional gain-of-function CaSR variants. This action helps to restore blood calcium levels, promote parathyroid hormone secretion, improve magnesium and phosphorus metabolism, and increase urinary calcium excretion. It is utilized in research for conditions such as osteoporosis and autosomal dominant hypocalcemia type 1.

  • Orally active
  • CaSR antagonist
  • Inhibits excessive CaSR activity
  • Restores blood calcium levels
  • Promotes parathyroid hormone secretion
  • Improves magnesium and phosphorus metabolism
  • Increases urinary calcium excretion

Catalog No. 50-003-54476


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