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Apexbio Technology LLC Endostatin (84-114)-NH2 (JKC367) 10mg
Supplier: Apexbio Technology LLC A110910
Endostatin 84-114 -NH2 (JKC367) is a C-terminal fragment derived from collagen XVIII with angiogenesis-inhibiting activity It functions by suppressing endothelial cell proliferation and migration required for neovascularization Endostatin 84-114 -NH2 exerts its biological activity primarily through the inhibition of angiogenesis In experimental tumor models continuous local administration of Endostatin 84-114 -NH2 has been reported to potentiate antitumor activities at lower dosages compared to intermittent injection Based on these pharmacological properties Endostatin 84-114 -NH2 (JKC367) holds research potential in oncology for tumor growth regulation metastatic process investigation and in vascular remodeling studies in cardiovascular disease models such as atherosclerosis
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