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Enzo Life Sciences ENMD-1068 (5mg)
SDP

Supplier:  Enzo Life Sciences BMLN1100005

Encompass_Preferred

Selective PAR-2 antagonist. Dose dependently inhibits calcium signaling in Lewis lung carcinoma cells stimulated with a soluble peptide PAR-2 agonist or trypsin, but not with a soluble PAR-1 agonist. Does not inhibit platelet aggregation stimulated by thrombin suggesting that it does not inhibit PAR-3 or PAR-4 signaling. Reduces TNF-α and IL-1β production from rheumatoid arthritis synovial primary cell culture and reduces joint swelling in a carageenan/kaolin-injected mouse model. Purity: ≥98% (TLC). Solubility: Soluble in water (5mg/ml), DMSO (2.5mg/ml) or 100% ethanol (5mg/ml). Long Term Storage: -20°C.

Catalog No. 50-201-1168


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