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Medchemexpress LLC ERD-3111 | 2832865-25-3 | 98.7% | 854.89 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1494801MG

Encompass_Preferred

ERD-3111 (Compound 44) is an orally active PROTAC ERα degrader with a DC50 of 0.5 nM. It has demonstrated efficacy in inhibiting tumor growth in the parental MCF-7 xenograft model, which has wild-type ER, as well as in two clinically relevant ESR1 mutated mice models. This compound holds potential for use in the research of ER+ breast cancer.

  • Orally active PROTAC ERα degrader.
  • Potent degradation with a DC50 of 0.5 nM.
  • Inhibits tumor growth in parental MCF-7 xenograft models.
  • Effective in models with wild-type ER and ESR1 mutated ER.
  • Applicable for research in ER+ breast cancer.

Catalog No. 50-003-60316


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