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Cayman Chemical Erlotinib Inhibitors
Supplier: Cayman Chemical 104835 G
An EGFR inhibitor (Ki = 2.7 nM); selective for EGFR over Src and Abl at 0.1 µM; induces caspase-3 and -7 activity in NCI H358 cells at 1 µM; reduces EGFR autophosphorylation in an HN-5 mouse xenograft model at 25 mg/kg
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