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Medchemexpress LLC ErSO-TFPy | 3035547-78-2 | C19H13F7N2O2 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1534685MG

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ErSO-TFPy (TEQ103) is an ERα+ tumor cell inhibitor that exhibits low nanomolar cytotoxic activity against ERα+ breast cancer cells. It functions by activating the sodium channel TRPM4, which leads to an imbalance of intracellular calcium and sodium ions. This dysregulation of calcium homeostasis in ERα+ tumor cells triggers the anticipatory unfolded protein response and induces rapid immune cell-independent necrotic cell death. ErSO-TFPy is suitable for research on estrogen receptor alpha positive breast cancer.

  • ERα+ tumor cell inhibitor.
  • Exhibits low nanomolar cytotoxic activity against ERα+ breast cancer cells.
  • Activates the sodium channel TRPM4.
  • Causes an imbalance of intracellular calcium and sodium ions.
  • Dysregulates calcium homeostasis in ERα+ tumor cells.
  • Triggers the anticipatory unfolded protein response.
  • Induces rapid immune cell-independent necrotic cell death.

Catalog No. 50-003-72916


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