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Apexbio Technology LLC Estriol 50-27-1 500mg
Supplier: Apexbio Technology LLC B1507500
Estriol (50-27-1) is a small-molecule estrogen receptor modulator targeting the G-protein coupled estrogen receptor (GPER) It is designed to antagonize GPER-dependent estrogen signaling thereby regulating estrogen-mediated cellular pathways independent of classical nuclear receptors Estriol exerts its biological activity primarily through antagonistic interaction with GPER In cell-based studies estriol demonstrates receptor-selective antagonistic activity in estrogen receptor-negative breast cancer cell lines Based on these pharmacological properties estriol holds research potential in oncology investigations involving hormone receptor-negative breast cancer and in the study of estrogen receptor-independent signaling pathways
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