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Medchemexpress LLC Ethyl maltol (Standard) | 4940-11-8 | 99.97% | 140.14 | 500 G
Supplier: Medchemexpress LLC HYW010320500G
Ethyl maltol is an orally active and significant food additive and flavor enhancer. It has been shown to be less toxic in rats and dogs compared to its homolog maltol. Research indicates that ethyl maltol can enhance copper-mediated cytotoxicity and induce apoptosis in lung epithelial cells.
- Induces cell apoptosis, oxidative stress, and DNA damage in copper-treated lung epithelial cells at 3 mM for 24 hours.
- Increased pATM phosphorylation level in copper-treated Calu-6 cells.
- Increased expression of ferritin light chain and hemeoxygenase in copper-treated Calu-6 cells.
- Safe in rats and dogs at oral administrations of 50-1000 mg/kg for 90 days-2 years, with less toxicity compared to maltol.
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