Cayman Chemical EtIcloprIdehydrochlorIde 10mg

Supplier:  Cayman Chemical 2911210 MG

A D2 and D3 receptor antagonist (Kis = 0.029 and 0.46 nM in MN9D mouse neuronal cells expressing rat D2 and human D3 receptors, respectively); selective for dopamine D2 and D3 receptors (IC50s = 1 and 113 nM, respectively) over dopamine D1, α2-adrenergic, and β-adrenergic, Histamine H1, and muscarinic receptors (IC50s = 700->100,000 nM), as well as 5-HT1 and 5-HT2 receptors (IC50s = 6,200 and 830, respectively) in radioligand binding assays; binds α1-ARs (IC50 = 110 nM); inhibits 7-OH-DPAT-induced stereotyped behavior in rats at 10 μg/kg; inhibits inhibits ketamine- and cocaine-induced hypermotility in rats at 20 and 50 μg/kg, respectively

Catalog No. 50-293-8064