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Medchemexpress LLC Evocalcet | 870964-67-3 | 99.3% | 374.48 | 5 MG
SDP

Supplier:  Medchemexpress LLC 5MGHY17613

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Evocalcet is an orally active calcium sensing receptor (CaSR) agonist. It inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells and is suitable for research related to hyperparathyroidism.

  • Orally active calcium sensing receptor (CaSR) agonist
  • Inhibits parathyroid hormone (PTH) secretion from parathyroid gland cells
  • Increases intracellular calcium ([Ca2+]i) in hCaR-HEK293 cells with an EC50 of 92.7 nM
  • Does not significantly inhibit cytochrome P450 (CYP) isozymes
  • Affects serum parathyroid hormone and calcium levels in vivo
  • Reduces serum parathyroid hormone and calcium levels and increases inorganic phosphorus levels in animal models of secondary hyperparathyroidism
  • Used for research of hyperparathyroidism

Catalog No. 50-003-93318


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