Medchemexpress LLC Exatecan mesylate | 169869-90-3 | 101.1% | 531.55 | 5 G

Supplier:  Medchemexpress LLC HY13631A5G

Exatecan mesylate is a DNA topoisomerase I inhibitor, exhibiting an IC50 of 2.2 μM (0.975 μg/mL) and is utilized in cancer research. It significantly inhibits the proliferation of various cancer cell lines, such as breast, colon, stomach, and lung cancer cells. In vivo studies demonstrate its antitumor activities in mouse models bearing tumor cells without causing toxic death, effectively inhibiting primary tumor growth and suppressing lymphatic and lung metastasis.

• Potent DNA topoisomerase I inhibitor
• Effective in inhibiting the proliferation of various cancer cell lines including breast, colon, stomach, and lung cancer cells
• Demonstrates antitumor activities in vivo without toxic effects
• Suppresses primary tumor growth and prevents metastasis
• Available in both solid and solution forms for research flexibility

Catalog No. 50-003-51453