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Medchemexpress LLC Farudodstat | 1035688-66-4 | 99.7% | 50 MG
SDP

Supplier:  Medchemexpress LLC HY12923950MG

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Farudodstat (ASLAN003) is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for the human DHODH enzyme. It inhibits protein synthesis by activating AP-1 transcription factors. Farudodstat induces apoptosis and significantly prolongs survival in acute myeloid leukemia (AML) xenograft mice.

  • Orally active and potent dihydroorotate dehydrogenase (DHODH) inhibitor
  • Inhibits protein synthesis via activation of AP-1 transcription factors
  • Induces apoptosis
  • Substantially prolongs survival in acute myeloid leukemia (AML) xenograft mice

Catalog No. 50-003-38851


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