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Medchemexpress LLC Fedratinib (hydrochloride hydrate) | 1374744-69-0 | MFCD28137677 | >98.0% | 615.6 g/mol | C27H40Cl2N6O4S | 5 G
SDP

Supplier:  Medchemexpress LLC HY10409A5G

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Fedratinib hydrochloride hydrate is a potent, selective, ATP-competitive, orally active JAK2 inhibitor used for research into JAK-STAT signaling and myeloproliferative disorders. It inhibits JAK2 and JAK2V617F with IC50 ≈ 3 nM and has been shown to induce cancer cell apoptosis, supporting its use in preclinical pathway and disease-model studies.

  • Potent JAK2 inhibition with IC50 of 3 nM
  • High selectivity versus JAK1 and JAK3
  • Suitable for myeloproliferative disorder and apoptosis research
  • Hydrochloride hydrate form for stable handling
  • Safety and handling details provided in the SDS

Catalog No. 50-002-42832


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