Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Fendiline hydrochloride | 13636-18-5
Supplier: Medchemexpress LLC 250MGHYB0984
Fendiline hydrochloride is a diphenylalkylamine type of antianginal agent that functions as an L-type calcium channel blocker. It also acts as a selective K-Ras inhibitor, without affecting H-Ras and N-Ras. Furthermore, it is identified as a STING agonist and has demonstrated the ability to inhibit the growth of various refractory cold tumors.
- Functions as an L-type calcium channel blocker (IC50 of 17 μM)
- Acts as a selective K-Ras inhibitor, without affecting H-Ras and N-Ras
- Inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM)
- Blocks proliferation of pancreatic, colon, lung, and endometrial cancer cell lines expressing oncogenic mutant K-Ras
- Identified as a STING agonist
- Inhibits growth of multiple refractory cold tumors (MC38, CT26, and B16F10)
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?