Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000375607

Medchemexpress LLC Fenretinide | 65646-68-6 | MFCD00792674 | C26H33NO2 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY15373

Encompass_Preferred

Fenretinide (4-HPR) is a synthetic retinoid derivative that binds to retinoic acid receptors (RAR) at concentrations necessary to induce cell death. It is intended for research use only.

  • Exerts acute and long-term antitumor activity in selected T-ALL cell lines.
  • Inhibits DES activity in CCRF-CEM leukemia cells, leading to increased dhCer content.
  • Protects insulin signaling by preventing lipid-induced reductions in insulin-stimulated glucose uptake.
  • Inhibits OVCAR-5 cell proliferation and viability.
  • Prevents endothelial cells from forming tubes at 1 microM.
  • Selectively inhibits ceramide accumulation in HFD-fed male C57Bl/6 mice.
  • Improves glucose tolerance and insulin sensitivity in mice.
  • Ketoconazole can increase 4-HPR plasma levels in NOD/SCID mice.

Catalog No. 50-003-75607


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.