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Cayman Chemical FerroLOXIN-1 10mg
Supplier: Cayman Chemical 3932510 MG
A 15-LO-2/PEBP1 and ferroptosis inhibitor; selectively inhibits the peroxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by the 15-LO-2/PEBP1 complex over 15-LO-2 alone in cell-free assays at 0.25 µM; inhibits RSL3-induced ferroptosis in primary human bronchial epithelial cells (IC50 = 84 nM); increases survival in a mouse model of total body irradiation at 25 mg/kg
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