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Enzo Life Sciences FH535 (5 mg). CAS: 108409-83-2

Supplier: Enzo Life Sciences BMLWN1120005

Antagonizes Wnt/β-catenin/Tcf-mediated transcription as well as PPARγ and δ activity. Able to inhibit the recruitment of the co-activators β-catenin and GRIP1, both of which are activators for both pathways. FH535 was toxic (LC50=5 to 15µM) to 10 of 12 carcinoma cell lines tested. A unique tool to study the relationship between Wnt and PPAR signaling pathways. Alternative name: N-(2-Methyl-4-nitrophenyl)-2,5-dichlorobenzenesulfonamide. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (20mg/ml). Long Term Storage: -20°C.
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