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Medchemexpress LLC FHT 2344 | 2468058-90-2 | >95.0% | 528.6 g·mol⁻1 | C23H24N6O5S2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY14945810MG

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FHT-2344 is a small-molecule chemical probe that potently inhibits the ATPase activity of SMARCA4 (BRG1) and SMARCA2 (BRM). It has been characterized in preclinical studies with anticancer activity and is supplied as a high-purity solid or as solutions for in vitro use.

  • Potent dual SMARCA2/SMARCA4 ATPase inhibition (SMARCA2 IC50 ≈ 0.013 μM; SMARCA4 IC50 ≈ 0.026 μM).
  • High selectivity versus CHD4 (no significant inhibition at ≤200 μM).
  • Validated in cell and xenograft models for transcriptional and antitumor effects.
  • Available as solid powder or 10 mM solution in DMSO for convenience.
  • High purity ≥95% by HPLC.
  • Molecular formula C23H24N6O5S2; molecular weight 528.6 g·mol⁻1.
  • Store at -20°C to preserve stability.

Catalog No. 50-002-86628


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