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Medchemexpress LLC Fibrinopeptide B, human TFA | 99.2% | 1666.58 | 10 MG
Supplier: Medchemexpress LLC HYP1493A10MG
Fibrinopeptide B, human TFA (FPB,human TFA) is a 14-amino acid peptide that is released from the amino-terminus of β-chains of fibrinogen by thrombin. It is intended for research use only. In vitro, Fibrinopeptide B, human causes directed cell migration of neutrophils (PMN) and fibroblasts at 10 nM concentration. It also exhibits potent chemotactic activity comparable to human complement (C5a), leukotriene B4 (LTB4), and formyl-methionylleucyl-phenylalanine (fMLP) for PMN, and to platelet-derived growth factor for fibroblasts. However, it is not chemotactic for monocytes and does not interact with PMN receptors for C5a, LTB4, or fMLP.
- 14-aa peptide
- Released from fibrinogen by thrombin
- Exhibits directed cell migration of neutrophils and fibroblasts in vitro
- Possesses potent chemotactic activity
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