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Medchemexpress LLC Fidaxomicin | 873857-62-6 | 99.8% | 1058.04 | 50 MG
Supplier: Medchemexpress LLC HY17580R50MG
Fidaxomicin is a macrocyclic antibiotic that acts as an orally active and potent RNA polymerase inhibitor. It exhibits a narrow spectrum of antibacterial activity and is particularly effective against *Clostridium difficile* (MIC90=0.12 μg/mL), making it suitable for research related to *Clostridium difficile* infection (CDI).
- Selectively eradicates pathogenic *Clostridium difficile* with minimal disruption to normal, healthy intestinal flora.
- Minimally impacts commensals and does not inhibit commonly cultured bowel commensals (MIC90 >1024 μg/mL).
- Completely prevents lethality and relapses in a hamster model for pseudomembranous colitis.
- Prevents development of antibiotic-induced *C. difficile* colitis in hamsters at doses as low as 0.2 mg/kg.
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