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Medchemexpress LLC Fingolimod | 162359-55-9 | 99.97% | 307.47 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY11063200MG

Encompass_Preferred

Fingolimod (FTY720 free base) is a brain-penetrant sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. It also acts as a PAK1 activator and an immunosuppressant. It promotes peripheral nerve regeneration and reduces neuroinflammation.

  • Brain-penetrant S1P antagonist
  • PAK1 activator
  • Immunosuppressant
  • Reduces LPA synthesis via inhibition of autotaxin
  • Significantly elevates axonal cAMP
  • Significantly reduces LPA levels in injured nerves
  • Improves myelin thickness
  • Increases nerve conduction
  • Improves nerve regeneration

Catalog No. 50-003-44246


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