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Medchemexpress LLC Fipronil (Standard) | 120068-37-3 | 99.5% | 50 MG
Supplier: Medchemexpress LLC HYB0822R50MG
Fipronil (Standard) is the analytical standard of Fipronil, intended for research and analytical applications. It is a broad-spectrum insecticide effective against various pests including Lepidoptera species, thrips, locusts, ants, cockroaches, fleas, and ticks.
- Fipronil selectively inhibits GABA receptors, with IC50s of 30 nM for cockroach GABA receptors and 1600 nM for rat GABA receptors.
- Glutamate-gated chloride channels (GluCls), found in cockroaches but not in mammals, are sensitive to Fipronil's blocking effect.
- It also induces apoptosis in HepG2 cells and promotes the expression of CYP1A1 and CYP3A4 mRNA in human hepatocytes.
- This compound is an analytical standard used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- The molecular weight is 437.15, and its chemical formula is C12H4Cl2F6N4OS.
- It appears as a white to off-white solid.
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