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TARGETMOL CHEMICALS INC FIVE1 5MG
Supplier: TARGETMOL CHEMICALS INC T96575MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. FiVe1 is a vimentin binding small molecule that promotes the disintegration and phosphorylation of vimentin in the metaphase leading to mitotic disasters polynuclearization and loss of cancer cell dryness. FiVe1 selectively and irreversibly inhibit the growth of mesenchymal transformed breast cancer cells (FOXC2-HMLER cell IC50=234nM) and soft tissue sarcomas of different histological subtypes. purity: 98%
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