Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Fludrocortisone | 127-31-1 | 99.0% | 25 MG
Supplier: Medchemexpress LLC 25MGHYB1203
Fludrocortisone is an orally active mineralocorticoid and glucocorticoid receptor agonist. It is used in research for conditions such as congenital adrenal hyperplasia, postural hypotension, and adrenal insufficiency. It works by:
- Suppressing pro-inflammatory cytokine expression and reducing CCL2, IL-6, IL-8 levels.
- Upregulating mineralocorticoid receptor (MR) expression.
- Inducing PI3K/Akt, GSK-3β, CREB, ERK1/2, mTOR phosphorylation.
- Blocking Tau hyperphosphorylation, preventing apoptosis, and promoting survival and proliferation.
- Enhancing renal sodium and water transport, increasing plasma volume and blood pressure, and reducing plasma potassium and renin activity.
- Stimulating erythropoietin expression.
- Modulating uterine receptivity genes and reversing MUC1 upregulation.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?