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Medchemexpress LLC Fluticasone furoate | 397864-44-7 | C27H29F3O6S | 50 MG
Supplier: Medchemexpress LLC HY1523450MG
Fluticasone furoate is a topical, intranasal, synthetic trifluorinated corticosteroid with potent anti-inflammatory and anti-asthmatic activity. It exhibits low systemic exposure and is primarily metabolized in the liver. It holds potential for the treatment of allergic rhinitis.
- Enhanced-affinity synthetic trifluorinated corticosteroid
- Potent anti-inflammatory and anti-asthmatic activity
- Low systemic exposure
- Potential for allergic rhinitis treatment
- Provided as a nasal spray for topical administration
- Inhibits tumor necrosis factor synthesis and action
- Effective in preventing damage to cultured human lung epithelial cells
- High plasma protein binding (99.4%)
- Extensive first-pass metabolism by CYP3A4
- Mainly excreted in the feces
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