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Apexbio Technology LLC Fluticasone propionate 80474-14-2 50mg
Supplier: Apexbio Technology LLC B209650
Fluticasone propionate is a synthetic glucocorticoid receptor (GR) agonist with high receptor selectivity and affinity It exerts anti-inflammatory and immunosuppressive actions by interacting with intracellular GR thereby influencing gene expression pathways and downstream cytokine responses This compound has been widely utilized in biomedical research to study inflammatory signaling mechanisms glucocorticoid receptor mediated transcriptional regulation and immune responses associated with asthma allergic rhinitis and related inflammatory diseases Reported in vitro studies demonstrate fluticasone propionate s GR agonist activity with an IC50 value in the subnanomolar range (approximately 0 5 nM) supporting its frequent utilization as a standard GR agonist in receptor-binding assays and inflammation-related experiments
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