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Apexbio Technology LLC Fmoc-Cys(Trt)-OH 103213-32-7 100g
Supplier: Apexbio Technology LLC A7874100000
Fmoc-Cys(Trt)-OH (CAS 103213-32-7) is a cysteine derivative commonly used in Fmoc-based solid-phase peptide synthesis The compound features a cysteine residue with its thiol group protected by a trityl (Trt) group and the amino group transiently masked by a fluorenylmethyloxycarbonyl (Fmoc) group During peptide assembly standard deprotection and coupling protocols enable stepwise peptide elongation After synthesis mild acidic conditions selectively remove the Trt group to yield free thiols facilitating disulfide bond formation Based on these properties Fmoc-Cys(Trt)-OH is extensively applied to the synthesis of cyclic peptides disulfide-constrained peptide analogs and therapeutically relevant proteins with defined disulfide linkages
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