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Bachem Fmoc-Glu(2-phenylisopropyl ester)-OH
SDP

Supplier:  Bachem 4025419.0001

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Fmoc-Glu(2-phenylisopropyl ester)-OH, 200616-39-3, C29H29NO6, Mr 487.55, 1g. Fmoc-Glu(OPp)-OH, Fmoc-Glu(O-2-PhiPr)-OH. Glu-derivative for the selective modification of the g-carboxyl group. The OPp group can be removed selectively in the presence of Boc/OtBu with 1% TFA/DCM. Ocampo et al. applied OPp protection during the synthesis of a peptide-oligonucleotide conjugate and cleaved it with 3% trichloroacetic acid in DCM. Tofteng et al. generated a backbone pyroglutamyl imide moiety from C-terminal Glu after selective on-resin OPp removal.

Catalog No. 50-258-658


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