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Medchemexpress LLC Fmoc-Val-Cit-PAB | 159858-22-7 | MFCD22417106 | 99.8% | 601.69 | C33H39N5O6 | 5 G

Supplier: Medchemexpress LLC HY193185G
Fmoc-Val-Cit-PAB is an Fmoc-protected valine-citrulline para-aminobenzyl (PAB) cleavable linker used in antibody-drug conjugate (ADC) synthesis. It provides a protease-sensitive Val-Cit cleavage site and a PAB self-immolative spacer to enable enzymatic release of payloads in lysosomes. The compound is supplied as a high-purity solid with good solubility in DMSO for conjugation workflows.
- Cleavable Val-Cit dipeptide recognized by cathepsin B
- PAB self-immolative spacer for rapid payload release
- Fmoc-protected amine compatible with standard peptide chemistry
- High purity (99.8%) suitable for research conjugation
- Soluble in DMSO (~83.33 mg/mL) with ultrasonic assistance
- Store protected from light; stable frozen in solution (-80°C, 6 months)
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