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Medchemexpress LLC Fmoc-Val-Cit-PAB-PNP | 863971-53-3 | MFCD22200278 | 99.6% | 766.80 | C40H42N6O10 | 1 G
Supplier: Medchemexpress LLC HY411891G
Fmoc-Val-Cit-PAB-PNP is a protease-cleavable antibody-drug conjugate (ADC) linker containing a valine-citrulline dipeptide and a p-aminobenzyl (PAB) self-immolative spacer; enzymatic cleavage releases carbamate-linked payloads for intracellular delivery.
- Contains Val-Cit dipeptide and p-aminobenzyl (PAB) spacer.
- Cleavable by lysosomal proteases such as cathepsin B.
- Enables enzymatic release of carbamate-linked payloads.
- Demonstrates high plasma stability compared with non-cleavable linkers.
- Supplied with high purity (99.6%).
- Available in milligram to gram scales for development and synthesis workflows.
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