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Cayman Chemical FondaparInuxsodIum salt 10mg
Supplier: Cayman Chemical 2403310 MG
An inhibitor of Factor Xa (IC50s = 40, 45, and 36 nM for human, rabbit, and rat enzymes, respectively); binds to antithrombin III (Kds = 48, 132, 78, and 50 nM for human, rabbit, baboon, and rat, respectively); inhibits thrombin generation through the extrinsic and intrinsic routes (IC50s = 0.3 and 2.8 µM, respectively); dose-dependently inhibits thrombus formation in a rabbit model of venous thrombosis with complete inhibition of clot formation at a dose of 200 UG/kg
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