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Cayman Chemical FTase InhIbItr IItrIfluoro 5mg
Supplier: Cayman Chemical 166075 MG
A cell-permeable analog of FPP that potently inhibits FTase (IC50 = 50-75 nM), preventing farnesylation of Ras; does not inhibit geranylgeranyl transferase at similar concentrations (IC50 > 100 µM); blocks Ras-mediated transformation of NIH 3T3 cells
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