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Medchemexpress LLC FTO-IN-8 | 2640366-38-5 | C19H23ClN2O2 | 50 MG
Supplier: Medchemexpress LLC HY15110650MG
FTO-IN-8 is an N6-methyladenosine demethylase (FTO) inhibitor with an IC50 value of 5.5 μM. This compound exhibits anti-cancer cell proliferative activity, making it suitable for research into cancer targeted therapy and metabolism.
- Inhibits proliferation of cancer cells (AGS, SNU-16, KATOIII)
- Shows no cytotoxicity to normal colonic cells (CCD-841CoN)
- Increases m6A and m6Am levels
- Inhibits Wnt/PI3K-Akt signaling in gastric cancer AGS cells
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