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Enzo Life Sciences Furin convertase inhibitor (chloromethylketone) (5mg)
SDP

Supplier:  Enzo Life Sciences ALX260022M005

Encompass_Preferred

Highly specific, potent, irreversible, and cell-permeable competitive inhibitor of proprotein convertases. Highly specific, potent, irreversible, and cell-permeable competitive inhibitor of proprotein convertases: furin/SPC1 (Ki~1nM), SPC2/PC2 (Ki=0.36nM), SPC3/PC1/PC3(Ki=2.0nM), SPC4/PACE4 (Ki=3.6nM), SPC6/PC5/PC6, and SPC7/LPC/PC7/PC8 (Ki=0.12nM). Because furin activates viral glycoproteins, this inhibitor is a useful antiviral agent. In addition, it inhibits furin-dependent pro-MMP-2 activation in various cell lines, including U87 and HT1080 cells. Typical concentration range used in tissue culture is 25-100µM. Alternative name: Decanoyl-Arg-Val-Lys-Arg-chloromethylketone, Dec-RVKR-CMK, TACE inhibitor. Formula: C34H66N11O5Cl . 3TFA. MW: 744.3 . 342.1. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO, methanol or water. Long Term Storage: -20°C.

Catalog No. 50-200-8228


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