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TARGETMOL CHEMICALS INC Fz7-21 5MG
SDP

Supplier:  TARGETMOL CHEMICALS INC TP12635MG

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Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-beta-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/beta-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of beta-catenin in mouse L cells (IC50=50 nM). Purity 99.8%

Catalog No. 50-288-0308


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